Substance Use & Recovery · samhsa.gov

Medications for Opioid Use Disorder - SAMHSA

September 21, 2026

# Medications for Opioid Use Disorder This Treatment Improvement Protocol (TIP) reviews the use of the three Food and Drug Administration (FDA)-approved medications used to treat OUD methadone, naltrexone, and buprenorphine and the other strategies and services needed to support recovery for people with OUD. #### Other Resources Like This [Substance Use Disorder](https://www.samhsa.gov/substance-use/recovery/recovery-resource-center?f%5B0%5D=issues_conditions_disorders%3A20317) [Substance Use or Misuse](https://www.samhsa.gov/substance-use/recovery/recovery-resource-center?f%5B0%5D=issues_con

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